International Journal of Hematology-Oncology and Stem Cell Research 2016. 10(2):111-114.

A Case of Multiple Myeloma Following Bladder Cancer
Hamid Shafi, Mohsen Vakili Sadeghi, Hosein Ghorbani, Majid Sharbatdaran


Second primary malignancy following multiple myeloma (MM) was reported several years ago. There are also rare reports of cases with synchronous MM and other malignancies. To our knowledge, only one case of MM following bladder cancer has been reported in the literature. Here, we report the second case occurred three months after diagnosis of bladder cancer.


bladder cancer; multiple myeloma; synchronous malignancies

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Kaushansky K, Lichtman M, Beutler E, et al. Williams Hematology: 8th edition; 2010; by The Mc Graw-Hill Companies; chapter 109, Myeloma.

Christou L, Tsiara S, Frangides Y, et al. Patients with multiple myeloma and solid tumors: six case reports. J Exp Clin Cancer Res. 1998 Jun; 17(2):239-42.

Agarwal R, Gupta R, Bhaskar A, et al. Synchronous presentation of multiple myeloma and lung cancer. J Clin Oncol. 2014; 32(24):5814-6.

Ji SH, Park JO, Lee J, et al. Three cases of synchronous solid tumor and multiple myeloma. Cancer Res Treat. 2004 Oct; 36(5): 338-40.

Lawrence L. Secondary Cancer Risk Found With Multiple Myeloma Maintenance Therapies. Rheumatology Network. 2013, May 02.

Yang J, Terebelo HR, Zonder JA. Secondary Primary Malignancies in Multiple Myeloma: An Old Nemesis Revisited. Hindawi Publishing Corporation Advances in Hematology. 2012: 1-9. DOI: 10.1155/2012/801495.

An HJ, Han KJ, Kim WI, et al. Multiple myeloma associate with adenocarcinoma of the stomach. Korean J Pathol. 1986; 20(2):191–194.

Todolí Parra JA, Campo López C, Segura Huerta A, et al. Association of multiple myeloma and solid neoplasms: analysis of 13 cases. Rev Clin Esp. 1999 Nov; 199(11):725-8.

Oshima K, Kanda Y, Nannya Y, et al. Clinical and pathologic findings in 52 consecutively autopsied cases with multiple myeloma. Am J Hematol. 2001 May; 67(1): 1-5

Wang Y, Peng F, Fu R, et al. Multiple Myeloma Following Bladder Cancer Successfully Treated with Bortezomib: A Case Report and Review of Literature. J Cancer Res Therap Oncol. 2014; 1:1-4.


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