Tehran University of Medical Sciences International Journal of Hematology-Oncology and Stem Cell Research 2008-2207 15 2 2021 04 11 75 76 Azin Alizadehasl Department of Cardio-Oncology Research, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences,Tehran, Iran Zohreh Rahbar Department of Adult Echocardiography, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran 2020 08 02 2020 11 21 Cancer treatment approaches are greatly improved in recent years. Myxomas are the most frequent intracardiac neoplasm, accounting for nearly 50% of all benign tumors. The left atrium with 75% of cases and the right atrium with 20% of cases are the most common locations of myxomas. Atrial myxomas are benign, slow-growing neoplasms that arise from the interatrial septum and extend into the left or right atrium. Right atrial myxomas may present as right-sided heart failure and pulmonary embolism. Breast cancer is the second most common cause of death among women worldwide. Eight percent of patients are presented with distant metastases. A large number of breast tumors are not random events, and some of them are due to the human genome alteration. Mammary carcinoma is a common familial cancer, which is transmitted in an autosomal dominant manner. We have noticed that patients with breast cancer visiting our cardio-oncology department are occasionally presented with cardiac myxoma. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1405 https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/download/1405/870