Tehran University of Medical Sciences International Journal of Hematology-Oncology and Stem Cell Research 2008-2207 2 1 2005 03 15 23 25 Kh Arjmandi Assistant professor of pediatric hematology and oncology, Iran University of Medical Sciences, Ali Asghar children’s Hospital M Faranoush Assistant professor of hematology and oncology, Semnan University of Medical Sciences, Amir al Momenin Hospital Gh Bahoush Assistant professor of pediatric hematology and oncology, Iran University of Medical Sciences, Ali Asghar children’s Hospital P Vossough Professor of pediatric hematology and oncology, Iran University of Medical Sciences, Ali Asghar children’s Hospital AA Hedayatiasl Fellowship of pediatric hematology and oncology, Iran University of Medical Sciences, Ali Asghar children’s Hospital Sh Ansari Assistant professor of pediatric hematology and oncology, Iran University of Medical Sciences, Ali Asghar children’s Hospital E Shahgholi Assistant professor of pediatric hematology and oncology, Tehran University of Medical Sciences, Bahrami children’s Hospital 2015 10 01 Background:  The hemoglobin disorders constitute the most prevalent group of monogenic disease A findings consis¬tent with this is a hemoglobin/G variant indicating that the patient has HbD/G trait. Hb D/G traits are clinically benign. In this study, the epidemiology of HbD/G was reviewed in a single institution in Iran. Methods and Materials: We conducted the epidemiological study at Aliasghar children's hospital and all patients with HbD/G were entered to this study. The hematological values, hemoglobin electrophoresis, peripheral blood smear and clinical findings were collected in the data special form. Results:  Among 11825 hemoglobin analysis performed, we detected 101 cases of hemoglobin D/G. There were 55.4% male and 44.6% female, median age 9±13.36 yrs. Homozygous of D/G was found in seven pa¬tients with splenomegaly, jaundice, mild anemia and Reticulocytosis. Heterozygote patients were as¬ymptomatic. There wasn't any correlation between HbD/G with serum ferritin, MCV, Hb and sex. Conclusion: In Iran HbD/G is relatively benign condition with mild anemia, Poikylocytosis and minimal hemolysis. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/178 https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/download/178/171