Tehran University of Medical Sciences International Journal of Hematology-Oncology and Stem Cell Research 2008-2207 3 1 2009 03 15 21 26 Kourosh Sayemiri Department of Biostatistics, School of Public Health, Tehran University of Medical Sciences, Iran. AND Department of social medicine, School of medicine, Ilam University of Medical Sciences, Iran MR Eshraghian Department of Biostatistics, School of Public Health, Tehran University of Medical Sciences, Iran Kazem Mohammad Department of Biostatistics, School of Public Health, Tehran University of Medical Sciences, Iran Kamran Alimoghaddam epartment of nutrition and biochemistry, School of Public Health, Tehran University of Medical Sciences, Iran A Rahimi Foroushani Department of Biostatistics, School of Public Health, Tehran University of Medical Sciences, Iran H Zeraati Department of Biostatistics, School of Public Health, Tehran University of Medical Sciences, Iran Ahmad Reza Shamshiri Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Iran K Djafarian Department of nutrition and biochemistry, School of Public Health, Tehran University of Medical Sciences, Iran Ardeshir Ghavamzadeh Department of nutrition and biochemistry, School of Public Health, Tehran University of Medical Sciences, Iran 2015 10 01 Introduction: This paper used Generalized Gamma (GG) distribution to find the predictive factors of overall survival (OS) after haematopoietic stem cell transplant (HSCT) in acute myeloid  leukemia patients. Methods: Discrimination among the exponential, Weibull, GG, log-logistic, and lognormal distributions was done using maximum likelihood and Akaike information criteria. Results: The 5-year OS in 301 patients was 65% (95%CI: 60.7-69.3). Peak mortality hazard occurred at months 6-7 after HSCT then, it was U Shape. The data was fitted by GG distribution better than other distributions. Univariate analysis using GG distribution showed a positive association between OS with dose of infused WBC (P=0.018), CD3 (p=0.001), no relapse (P<0.001), cGVHD (P<0.001), and platelet recovery (P<0.001). Multivariate analysis indicated that, OS has relationship with relapse (P<0.001), platelet recovery (P=0.004), disease status at transplant (P=0.036) and aGVHD (P=0.036). Conclusion: We showed that GG distribution can be a useful tool for recognizing prognostic factors of OS in AML patients. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/203 https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/download/203/196