Tehran University of Medical Sciences International Journal of Hematology-Oncology and Stem Cell Research 2008-2207 3 2 2009 06 15 18 20 Andisheh Ghashghaie Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran Kamran Alimoghaddam Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran Mohammad Reza Ostadali Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran Hamid-o-allah Ghaffari Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran L Khansari Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran M Sadraee Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran E Mirrasekhian Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran Iranna Mohyedin Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran F Raoofi Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran Z Noori Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran H Yaghmaian Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran H Eshaghi Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran Ardeshir Ghavamzadeh Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Dr. Shariati Hospital, Tehran, Iran 2015 10 01 Introduction: Human Leukocyte Antigen (HLA) genes are the most polymorphic loci in the human genome. They predict the outcome of transplantation by detecting self from non-self antigens. The best use of HLA typing is to find a HLA-match donor for BMT candidate patients. Evidence suggests that matching unrelated donors and recipients for HLA-A, -B and -DRB1 loci is a prediction for an improved outcome. Methods and materials: HLA-A and -B of six hundred Iranian cord blood samples were typed by PCR-SSP method and the frequency of loci were estimated. Results: The most frequent alleles were A*02(18.16), A*24(16.41), B*35(21.66) and B*51(13.35), respectively. Discussion: Our HLA typing data show similarity between neighbor and related countries and Caucasians. Identifying HLA alleles helps to find suitable donors for patients in need of hematopoietic stem cell transplantation. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/211 https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/download/211/204