Tehran University of Medical Sciences International Journal of Hematology-Oncology and Stem Cell Research 2008-2207 4 1 2010 03 15 28 30 Ali Naderi Pediatric Hematology- Oncology Department, Kerman University of Medical Sciences, Kerman, Iran Mohmmadreza Ebadzadeh Urology Department, Kerman University of Medical Sciences, Kerman, Iran Jalal Azmandyan Nephrology, Kerman University of Medical Sciences, Kerman, Iran Razieh Fayazfar Hemophilia center of Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran Elham Ahmadi Pediatric Ward, Kerman University of Medical Sciences, Kerman, Iran Ali Rikhtehgaran Tehrani Researcher, Kerman University of Medical Sciences, Kerman, Iran 2015 10 01 Introduction: The prevalence of rare bleeding disorders, including combined factor V+VIII deficiency are higher in Iran than in developed countries. There are only a few reports which have been written concerning kidney transplantation in the patients suffering from these disorders. Case report: A 22-year old girl, with a known case of combined factor V+VIII deficiency, a history of bladder stone surgery, postoperative bleeding and a need for hemodialysis due to renal failure was admitted for allograft kidney transplantation. The patient received fresh-frozen plasma and factor VIII, according to individualized protocol before, during and after the course of the transplantation. The function of the grafted kidney was very good nine months post-transplantation. Discussion: Only heparin was used during hemodialysis. It has been shown that allograft kidney transplantation can be performed in rare bleeding disorders with good replacement therapy without any complications. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/238 https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/download/238/231