Tehran University of Medical Sciences International Journal of Hematology-Oncology and Stem Cell Research 2008-2207 9 1 2015 03 15 22 25 Maryam Mobini Diabetes research center, Mazandaran University of Medical Sciences, Sari, Iran. Ramin Shekarriz Department of Hematology and Oncology, Imam khomeini hospital, Mazandaran University of Medical sciences, Sari, Iran. Reza Ali Mohammad Pour Biostatistics department, Faculty of health, Diabetes research center, Mazandaran University of Medical Sciences, Sari, Iran. Shahrzad Zakeri Medical student, Mazandaran University of Medical Sciences, Sari, Iran. 2015 10 14 Background: The aim of this study was to determine the prevalence and characteristics of rheumatologic manifestations associated with MDS. Methods: Eighty patients with MDS were evaluated by history and physical examination for inflammatory rheumatologic disorders from Jan 2013 to May 2014. Patients who had any signs or symptoms of rheumatologic disorders underwent evaluation by laboratory tests. Patients with and without inflammatory rheumatic disorders were compared for their characteristics. Results: Of 80 participants with MDS, 9 (11.3%) patients were diagnosed as having rheumatic disorders. MDS patients with or without rheumatologic disorder were similar in demographic and hematologic parameters, except age which was lower in patients with rheumatologic disorders. (p=0.016). In younger patients, refractory cytopenia and refractory cytopenia with multilinage dysplasia were more prevalent. Conclusion: The findings of this study indicate that rheumatologic manifestations may be present in MDS patients. Younger patients are more prone to the occurrence of MDS and rheumatic disorders. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/398 https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/download/398/399