Tehran University of Medical Sciences International Journal of Hematology-Oncology and Stem Cell Research 2008-2207 7 2 2013 06 15 37 41 Naser Aghamohammadzadeh Assistant Professor, Endocrinology Department, Tabriz University of Medical Sciences, Tabriz, Iran. Afsaneh Faraji Medical Student, Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran. Farshid Bozorgi Anatomical and Clinical Pathologist, Tabriz University of Medical Sciences, Tabriz, Iran. Ismail Faraji Internist, fellow of Endocrinology, Tabriz University of Medical Sciences, Tabriz, Iran. Majid Moghadaszadeh Resident of Internal Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. 2015 10 14 Adrenocortical carcinoma (ACC) is a rare tumor and usually a fatal disease which can develop at any age in either sex. Differential diagnosis between malignant and benign adrenal mass is not easy which leads to significant clinical challenge for optimal treatment. Here we report a 22-year-old woman diagnosed with primary hyper aldostronism initially but disease relapsed during six months and magnetic resonance imaging revealed tumor with metastasis to the liver. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/452 https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/download/452/345