Rare Presentation of Refractory Thrombotic Thrombocytopenic Purpura: Jejunal Stricture

  • Prabath K. Abeysundara Post graduate institute of Medicine, University of colombo, Colombo, Sri Lanka
  • Inoshi Atukorala Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
  • K. P. C. Dalpatadu Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
  • Karthiha Balendran Post graduate institute of Medicine, University of Colombo, Colombo, Sri Lanka
  • M. D. S. A. Dilrukshi Post graduate institute of medicine, University of Colombo, Colombo, Sri Lanka
  • G M O Fernando Post graduate institute of medicine, University of Colombo, Colombo, Sri Lanka
Keywords: TTP, Chron’s- disease

Abstract

Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis. Thrombotic thrombocytopenic purpura was first described in 1924 by Moschowitz as a disease presenting with a pentad of signs and symptoms (anemia, thrombocytopenia, fever, hemiparesis and hematuria). Previous studies have described atypical manifestations of thrombotic thrombocytopenic purpura such as hemolysis, anemia and thrombosis.

Author Biographies

Prabath K. Abeysundara, Post graduate institute of Medicine, University of colombo, Colombo, Sri Lanka
Registrar in General Medicine
Inoshi Atukorala, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
Senior Lecturer
K. P. C. Dalpatadu, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
Senior Lecturer
Karthiha Balendran, Post graduate institute of Medicine, University of Colombo, Colombo, Sri Lanka
Registrar in General Medicine
M. D. S. A. Dilrukshi, Post graduate institute of medicine, University of Colombo, Colombo, Sri Lanka
Registrar in General Medicine
G M O Fernando, Post graduate institute of medicine, University of Colombo, Colombo, Sri Lanka
Registrar in Dermatology

References

Moschcowitz E. Hyaline thrombosis of the terminal arterioles and capillaries: a hitherto undescribed disease. Proc N Y Pathol Soc; 1924; 24: 21-24.

George JN. How I treat patients with thrombotic thrombocytopenic purpura. Blood. 2010; 116(20):4060-4069.

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Winwood PJ, Iredale JP, Williamson PJ, et al. Thrombotic thrombocytopenic purpura mimicking acute small bowel Crohn's disease. Gut. 1992; 33(6):857-9.

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Griffin D, Al-Nouri ZL, Muthurajah D, et al. First symptoms in patients with thrombotic thrombocytopenic purpura: what are they and when do they occur?. Transfusion. 2013. 53(1): 235–237.

Published
2017-10-01
How to Cite
1.
Abeysundara P, Atukorala I, C. Dalpatadu K, Balendran K, S. A. Dilrukshi M, O Fernando G. Rare Presentation of Refractory Thrombotic Thrombocytopenic Purpura: Jejunal Stricture. ijhoscr. 11(4):293-5.
Section
Case Report(s)