Pattern of Kebab Intake as a Potential Carcinogenic Risk Factor in Adults of Kermanshah, Iran: 2015
AbstractBackground: Epidemiologic studies indicated that dietary pattern plays a determinant role in cancer incidence. They also indicated that 1/3 of cancers are associated to foods. Diet contains different carcinogenic agents: naturally occurring chemicals, synthetic components and compounds produced during cooking such as kebab. This traditional food is one of the most popular foods in the Middle East, particularly in Iran. Red meat, especially lamb or veal, is the most common meat used in preparation of kebab. Since kebab is considered as a food containing carcinogenic compounds, so the purpose of this study was to assess the consumption pattern of kebab in a sample of Iranian adults and its relationship with demographic characteristics.Materials and Methods: This cross-sectional study was conducted between March and April 2015 on 705 Iranian adults who were living in Kermanshah province in the west of Iran. Subjects were selected randomly from different districts of Kermanshah. Data were collected through a questionnaire survey which had been designed by academic members of Department of Nutrition at Kermanshah University of Medical Sciences. Data analysis was performed using SPSS Version 20. The results were expressed as mean ± SD. Student’s t-test, ANOVA and chi-square tests were performed to compare the study groups. The normality of data was assessed using the Kolmogorov-Smirnov test. All results were analyzed using a significance level of P <0.05.Results: The results indicated that nearly 60% of subjects have a high tendency to consume kebab. The average of kebab consumption among the participants in this study was 4 times per month. Nearly, 85% of study participants tended to consume kebab with a large amount of salt. The chi-square test determined the significant difference between education and tendency to consume kebab; individuals with higher level of education had more tendency to consume kebab than those having lower level of education (p=0.021). In this study, 93.9% of participants used charcoal, a cooking fuel, to prepare kebab.Conclusion: The results of this study point out that the study participants, regardless of socio-economic status, consume high amounts of kebab, and thus this unhealthy eating habit will increase the risk of carcinogenesis. Therefore, the immediate attention of Public Health Officials is required.
Hajjar RR, Atli T, Al-Mandhari Z, et al. Prevalence of aging population in the Middle East and its implications on cancer incidence and care. Ann Oncol. 2013; 24(7): 11–24.
Kizil M, Oz F, Besler HT. A Review on the Formation of Carcinogenic/Mutagenic Heterocyclic Aromatic Amines. J Food Process Technol. 2011; 2(5):1-5.
Fitzmaurice C, Dicker D, Pain A, et al. The Global Burden of Cancer 2013. JAMA Oncol. 2015; 1(4): 505–27.
Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380(9859):2095-128.
Viegas O, Novo P, Pinto E, et al. Effect of charcoal types and grilling conditions on formation of heterocyclic aromatic amines (HAs) and polycyclic aromatic hydrocarbons (PAHs) in grilled muscle foods. Food Chem Toxicol. 2012; 50(6):2128-34.
Taner S, Pekey B, Pekey H. Fine particulate matter in the indoor air of barbeque restaurants: Elemental compositions, sources and health risks. Sci Total Environ. 2013; 454-455:79-87.
Farhadian A, Jinap S. Effects of meat preheating and wrapping on the levels of polycyclic aromatic hydrocarbons in charcoal-grilled meat, Food Chemistry.2011; 124 (1): 141–146.
Farhadian A, Jinap S. Determination of polycyclic aromatic hydrocarbons in grilled meat. Food Control. 2010; 21 (5):606–610.
Hu FB. Dietary pattern analysis: a new direction in nutritional epidemiology. Curr Opin Lipidol. 2002; 13(1):3-9.
Jacobs DR Jr, Steffen LM. Nutrients, foods, and dietary patterns as exposures in research: a framework for food synergy. Am J Clin Nutr. 2003; 78 (Suppl):508S–513S.
Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study. Lancet. 2012; 380(9859):2095-128.
Kamankesh M, Mohammadi A, Hosseini H, et al. Rapid determination of polycyclic aromatic hydrocarbons in grilled meat using microwave-assisted extraction and dispersive liquid-liquid microextraction coupled to gas chromatography-mass spectrometry. Meat Sci. 2015; 103: 61-7.
Turesky RJ. Formation and biochemistry of carcinogenic heterocyclic aromatic amines in cooked meats. Toxicol Lett. 2007; 168(3):219-27.
Kao TH, Chen S, Huang CW, et al. Occurrence and exposure to polycyclic aromatic hydrocarbon in kindling-free-charcoal grilled meat products in Taiwan. Food Chem Toxicol. 2014; 71:149-58.
Ruan ED, Juárez M, Thacker R, et al. Dietary vitamin E effects on the formation of heterocyclic amines in grilled lean beef. Meat Sci. 2014; 96(2 Pt A):849-53.
Cross AJ, Ferrucci LM, Risch A, et al. A large prospective study of meat consumption and colorectal cancer risk: An investigation of potential mechanisms underlying this association. Cancer Res. 2010; 70(6):2406-14.
Anderson KE, Sinha R, Kulldorff M, et al. Meat intake and cooking techniques: Associations with pancreatic cancer. Mutat Res. 2002; 506-507:225-31.
Stolzenberg-Solomon RZ, Cross AJ, Silverman DT, et al. Meat and meat-mutagen intake and pancreatic cancer risk in the NIH-AARP cohort. Cancer Epidemiol Biomarkers Prev. 2007; 16(12):2664-75.
Cross AJ, Peters U, Kirsh VA, et al. A prospective study of meat and meat mutagens and prostate cancer risk. Cancer Res. 2005; 65(24):11779–84.
Sinha R, Park Y, Graubard BI, et al. Meat and meat-related compounds and risk of prostate cancer in a large prospective cohort study in the United States. Am J Epidemiol. 2009; 170(9):1165-77.
Navarro A, Muñoz SE, Lantieri MJ. Meat Cooking Habits and Risk of Colorectal Cancer in Córdoba, Argentina. Nutrition. 2004; 20(10):873-7.
Knize MG, Felton JS. Formation and human risk of carcinogenic heterocyclic amines formed from natural precursors in meat. Nutr Rev. 2005; 63(5):158-65.