Sleep Quality and Fatigue among Breast Cancer Patients Undergoing Chemotherapy
Abstract
Background: Breast cancer survivors make up a growing population facing treatment that poses long – standing adverse effects including chemotherapy- related sleep disorders and fatigue. There is limited knowledge of patients' lived experiences of chemotherapy- induced sleep disorders and fatigue. The aim of this study was to explore sleep quality and fatigue among breast cancer patients undergoing chemotherapy
Materials and Methods: One hundred fifteen patients were included in this census-based cross-sectional study. Data were collected through the Pittsburgh Sleep Quality Index and Brief Fatigue Inventory four days after the chemotherapy session. Statistical analysis was carried out using SPSS software version 13 and P<0.05 was considered significant in all tests.
Results: The mean hours of sleep were 5.6±1.83 in the range of 2 to 10 hours. The mean score of fatigue of participants was 5.59±1.67. Based on the cutting point, 57.4%, 20.9%, and 21.7% of participants had a moderate (4-6.9), mild (0.1-3.9), and severe (7-9.9) level of fatigue, respectively. The mean score of sleep quality among the participants was equal to 14.06±3.06, with a maximum and minimum of 7 and 21. The results of Spearman correlation coefficient showed that there is a significant relationship between fatigue and quality of sleep )0.210).
Conclusion: Since the study findings revealed that patients with breast cancer undergoing chemotherapy experience different degrees of sleep disorders and fatigue and due to the little attention paid to this issue in the medical field, there is a need for more detailed studies to improve the quality of sleep and reduce fatigue in these patients.
2. Baade PD, Dasgupta P, Youl PH, et al. Geographical inequalities in surgical treatment for localized female breast cancer, Queensland, Australia 1997–2011: improvements over time but inequalities remain. Int J Environ Res Public Health. 2016; 13(7). pii: E729.
3. Lu C, Sun H, Huang J, et al. Long-Term Sleep Duration as a Risk Factor for Breast Cancer: Evidence from a Systematic Review and Dose-Response Meta-Analysis. Biomed Res Int. 2017;2017:4845059.
4. Hosseinzadeh M, Eivazi Ziaei J, Mahdavi N, et al. Risk factors for breast cancer in Iranian women: a hospital-based case-control study in tabriz, iran. J Breast Cancer. 2014; 17(3): 236–243.
5. Sadoughi F, Afshar HL, Olfatbakhsh A, et al. Application of canonical correlation analysis for detecting risk factors leading to recurrence of breast cancer. Iran Red Crescent Med J. 2016; 18(3): e23131.
6. Fakih R, Rahal M, Hilal L, et al. Prevalence and severity of sleep disturbances among patients with early breast cancer. Indian J Palliat Care. 2018; 24(1):35-38.
7. Liu L, Mills PJ, Rissling M, et al. Fatigue and sleep quality are associated with changes in inflammatory markers in breast cancer patients undergoing chemotherapy. Brain Behav Immun. 2012; 26(5):706-13.
8. Trudel-Fitzgerald C, Zhou ES, Poole EM, et al. Sleep and survival among women with breast cancer: 30 years of follow-up within the Nurses’ Health Study. Br J Cancer. 2017;116(9):1239-1246.
9. Sanford SD, Wagner LI, Beaumont JL, et al. Longitudinal prospective assessment of sleep quality: before, during, and after adjuvant chemotherapy for breast cancer. Support Care Cancer. 2013; 21(4):959-67.
10. Zhang B, Dong Jn, Sun P, et al. Effect of therapeutic care for treating fatigue in patients with breast cancer receiving chemotherapy. Medicine (Baltimore). 2017; 96(33):e7750.
11. Swen M, Mann A, Paxton RJ, et al. Do Cancer-Related Fatigue and Physical Activity Vary by Age for Black Women With a History of Breast Cancer? Prev Chronic Dis . 2017;14: 170128
12. Jassim GA, Whitford DL. Quality of life of Bahraini women with breast cancer: a cross sectional study. BMC Cancer. 2013;13:212.
13. Abu-Helalah M, Al-Hanaqta M, Alshraideh H, et al. Quality of life and psychological well-being of breast cancer survivors in Jordan. Asian Pac J Cancer Prev. 2014;15(14):5927-36.
14. Halawi R, Aldin ES, Baydoun A, et al. Physical symptom profile for adult cancer inpatients at a Lebanese cancer unit. European journal of internal medicine. Eur J Intern Med. 2012; 23(8):e185-9.
15. Farrahi Moghaddam J, Nakhaee N, Sheibani V, et al. Reliability and validity of the Persian version of the Pittsburgh Sleep Quality Index (PSQI-P). Sleep Breath. 2012;16(1):79-82.
16. Paramita N, Nusdwinuringtyas N, Nuhonni SA, et al. Validity and Reliability of the Indonesian Version of the Brief Fatigue Inventory in Cancer Patients. J Pain Symptom Manage. 2016; 52(5):744-751.
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Issue | Vol 13, No 4 (2019) | |
Section | Original Article(s) | |
DOI | https://doi.org/10.18502/ijhoscr.v13i4.1894 | |
Keywords | ||
Sleep; Fatigue, Breast; Cancer; Chemotherapy |
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