Resiliency, the Lived Experience of Patients Undergoing Hematopoietic Stem Cell Transplantation

  • Ali Karimi Rozveh School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  • Alireza Nikbakht Nasrabadi School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  • Shahrzad Ghiyasvandian School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  • Leila Sayadi School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Vaezi Hematology- Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran
  • Reza Nabi Amjad Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
Lived experience; Hematopoetic stem cells; resiliency; phenomenology


Background: Hematopoetic stem cell transplantation is considered as a standard treatment for cancer patients to stay hopeful toward treatment outcome. However, these patients experience many complications which might affect different aspects of their life. The aim of this study was to investigate the lived experience of patients after hematopoetic stem cell transplantation and introduce supportive care strategies.

Materials and Methods: In this study, Van Manen’s Hermeneutic phenomenological approach was used. Eleven patients (7 males and 4 females) were chosen by targeted sampling from visitors of Shariati Hospital’s outpatient clinic. Semi-structured interviews were conducted and the final data were analyzed by MAXQDA 10 software.

Results: Data analysis revealed that the main theme was resiliency with two sub-themes of “not surrendering to disease” and “feeling closer to God”.

Conclusion: Participants declared that transplantation was like a second chance for life and considered this opportunity as a gift from God to overcome their disease. According to our findings, spirituality aids can help patients control the disturbances following HSCT and health professionals can use constructive strategies to support patients with spiritual needs.


1. Morrison CF, Martsolf DM, Wehrkamp N, et al. Medication adherence in hematopoietic stem cell transplantation: a review of the literature. Biol Blood Marrow Transplant. 2017;23(4):562-568.
2. Ghavamzadeh A, Alimoghaddam K, Jahani M, et al. Stem Cell Transplantation in Iran; 1991 until 2009. Int J Hematol Oncol Stem Cell Res. 2009;3(1):27-33.
3. Ghavamzadeh A, Alimoghaddam K, Jahani M, et al. Stem cell transplantation; Iranian experience. Arch Iran Med. 2009;12(1):69-72.
4. Ghavamzadeh A, Alimoghaddam K, Ghaffari F, et al. Twenty Years of Experience on Stem Cell Transplantation in Iran.Iran Red Crescent Med J. 2013;15(2):93-100.
5. Sun C-L, Francisco L, Baker KS, et al. Adverse psychological outcomes in long-term survivors of hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study. Blood. 2011; 118(17): 4723–4731.
6. Stephens M. The lived experience post-autologous haematopoietic stem cell transplant (HSCT): a phenomenological study. Eur J Oncol Nurs. 2005;9(3):204-15.
7. Ariza-Heredia EJ, Chemaly RF. Infection control practices in patients with hematological malignancies and multidrug-resistant organisms: special considerations and challenges.Clin Lymphoma Myeloma Leuk. 2014;14 Suppl:S104-10.
8. Lin T-LLK-PLS-PH-R. Lived Experienceof Patients Undergoing Allogeneic Peripheral Hematopoietic Stem Cell Transplant. International Journal of Research In Medical and Health Sciences. 2014;4(2):36-46.
9. Jones C, Chapman YB. The lived experience of seven people treated with autologous bone marrow/peripheral blood stem cell transplant. Int J Nurs Pract. 2000;6(3):153-9.
10. Zamanzadeh V, Valizadeh L, Sayadi L, et al. Life in Limbo: Experiences of Iranian Hematopoietic Stem Cell Transplantation Recipient Patients and Nurses in a Qualitative Study. Int J Hematol Oncol Stem Cell Res. 2013;7(3):25-33.
11. Zamanzadeh V, Azimzadeh R, Rahmani A, et al. Oncology patients' and professional nurses' perceptions of important nurse caring behaviors.BMC Nurs. 2010 Jun 15;9:10.
12. Van Rooyen D, Le Roux L, Kotzé W. The experiential world of the oncology nurse. Health SA Gesondheid. 2008;13(3):18-30.
13. Huang YP, Kellett U, Wang SY, et al. Experience of Nurses Caring for Child With Hematopoietic Stem Cell Transplantation in General Pediatric Ward: A Descriptive Phenomenological Approach. Cancer Nurs. 2014;37(5):E32-9.
14. Van Manen M. Researching lived experience: Human science for an action sensitive pedagogy: Routledge; 2016.
15. Van Manen M. Writing qualitatively, or the demands of writing.Qual Health Res. 2006; 16(5):713-22.
16. Dowling M. From Husserl to van Manen. A review of different phenomenological approaches. Int J Nurs Stud. 2007 Jan;44(1):131-42.
17. Rosenberg AR, Syrjala KL, Martin PJ, et al. Resilience, health, and quality of life among long‐term survivors of hematopoietic cell transplantation. Cancer. 2015;121(23):4250-7.
18. Gilfillan R. Quality of life following haematopoietic stem cell transplant among recipients aged over 50 years: an interpretative phenomenological analysis: University of Glasgow; 2011.
19. Smith GL. The patient experience of stem cell transplant and how survivor testimonies influence this: an interview study: University of Leeds; 2017.
20. Coolbrandt A, Grypdonck MH. Keeping courage during stem cell transplantation: a qualitative research.Eur J Oncol Nurs. 2010 Jul;14(3):218-23.
21. Alnasser Q, Abu Kharmah SD, Attia M, et al. The lived experience of autologous stem cell‐transplanted patients: Post‐transplantation and before discharge.J Clin Nurs. 2018; 27(7-8):e1508-e1518.
22. Alaloul F, Schreiber JA, Al Nusairat TS, et al. Spirituality in Arab Muslim Hematopoietic Stem Cell Transplantation Survivors: A Qualitative Approach. Cancer Nurs. 2016 Sep-Oct;39(5):E39-47.
23. Sirilla J, Overcash J. Quality of life (QOL), supportive care, and spirituality in hematopoietic stem cell transplant (HSCT) patients.Support Care Cancer. 2013 Apr;21(4):1137-44.
How to Cite
Karimi Rozveh A, Nasrabadi A, Ghiyasvandian S, Sayadi L, Vaezi M, Amjad R. Resiliency, the Lived Experience of Patients Undergoing Hematopoietic Stem Cell Transplantation. Int J Hematol Oncol Stem Cell Res. 13(4):189-195.
Original Article(s)