Case Report

Treatment of Acute Lymphoid Leukemia Refractory to Classic First-Line and Rescue Protocols


Acute Lymphoblastic Leukemia is a very aggressive malignant disorder of lymphoid cells in adults, with recurrence (30 to 60% of the cases) after the initial treatment. Until this moment, there is no gold standard therapy for the treatment of adult patients with acute relapsed/refractory lymphoblastic leukemia. In this case report, we describe two cases of relapsed leukemia: one of lymphocytic leukemia B and one of trilineage leukemia, which presented a satisfactory response to treatment with Bortezomib associated with Vincristine, Dexamethasone, and Bendamustine.

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IssueVol 14, No 2 (2020) QRcode
SectionCase Report(s)
Acute Lymphoblastic Leukemia; Lymphoid cells; Relapsed leukemia

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How to Cite
Russo F, Macedo MC, Fernandes P, Okada L, da Silva L, Simões C, Cavalcante J, Simões A, Almeida M, Lopes M, da Silva R. Treatment of Acute Lymphoid Leukemia Refractory to Classic First-Line and Rescue Protocols. Int J Hematol Oncol Stem Cell Res. 14(2):123-126.