Case Report

A Case of Systemic Lupus Erythematosus Presenting as Pure Red Cell Aplasia


Pure red cell aplasia (PRCA) is an uncommon condition, which is rarely associated with Systemic Lupus Erythematosus (SLE). Prompt identification and management of the underlying SLE results in the correction of anemia. We report the case of a young female who presented due to severe anemia for the last two years. The cause of her anemia on initial investigations was not elicited in these two years, during which response to hematinics was poor and she remained transfusion dependent. Bone marrow biopsy showed PRCA after which autoimmune workup revealed SLE. Subsequently, treatment of SLE with steroids led to normalization of hemoglobin levels within a follow-up period of three months.

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IssueVol 15, No 2 (2021) QRcode
SectionCase Report(s)
Pure red cell aplasia; Systemic lupus erythematosus; Diagnosis; Anemia

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Saeed M, Sharif F, Ijaz M, Kamran S. A Case of Systemic Lupus Erythematosus Presenting as Pure Red Cell Aplasia. Int J Hematol Oncol Stem Cell Res. 2021;15(2):135-138.