Articles

Protective Isolation for Patients with Haematological Malignancies: A Pilot Study Investigating Patients’ Distress and Use of Time

Abstract

Background: Patients with haematological malignancies are often hospitalized in protective isolation until full neutrophil recovery in order to prevent infections. This descriptive pilot study evaluate the level of isolation-related distress and the use of free time in a sample of Italian onco-haematological patients who were hospitalized in protective isolation.
Materials and Methods: Participants were 18 patients hospitalized in hematologic ward to receive induction therapy (n=12) or autologous stem cell transplant (n=6). They completed a self-report questionnaire before discharge.
Results: Participants reported a moderate level of isolation-related distress, anxiety, and boredom: the more the anxiety and the boredom, the more the distress (r=.77; P<.001), (r=.79; P<.001), respectively. The activities performed during isolation were: watching TV (72.2%), reading (55.6%), thinking (33.3%), surfing in Internet or using PC (33.3%), and playing games or making cross-words (16.7%). Participants who reported pessimistic thinking had higher isolation-related distress (P=.004) as well as anxiety (P<.001) and boredom (P=.001).
Conclusion: Haematology Units should support isolated patients in spending their time in recreational activities, allowing more contacts with immediate relatives and friends, providing free TV and Wi-Fi connection inside the room. In addition, patients should have to keep themselves physically active. Isolation-related distress could also be reduced by providing psychological support.

Saria M. Preventing and managing infections in neutropenic stem cell transplantation recipients: evidence-based review. Clin J Oncol Nurs. 2011; 15(2):133-9

Yokoe D, Casper C, Dubberke E, et al. Infection prevention and control in health-care facilities in which hematopoietic cell transplant recipients are treated. Bone Marrow Transplant. 2009. 44(8): 495-507.

Vokurka S, Bystrická E, Svoboda T, et al. The availability of HEPA-filtered rooms and the incidence of pneumonia in patients after haematopoietic stem cell transplantation (HSCT): results from a prospective, multicentre, eastern European study. J Clin Nurs. 2014; 23(11-12):1648-52

Mank A, van der Lelie H. Is there still an indication for nursing patients with prolonged neutropenia in protective isolation? An evidence-based nursing and medical study of 4 years experience for nursing patients with neutropenia without isolation. Eur J Oncol Nurs. 2003; 7(1): 17-23.

Caselli D, Cesaro S, Livadiotti S, et al. Preventing transmission of infectious agents in the pediatric in-patients hematology-oncology setting: What is the role for non-pharmacological prophylaxis? Pediatr Rep. 2011; 3(1):e9.

Hayes-Lattin B, Leis JF, Maziarz RT. Isolation in the allogeneic transplant environment: How protective is it? Bone Marrow Transplant. 2005; 36(5):373-81

Ariza-Heredia EJ, Chemaly RF. Infection control practices in patients with hematological malignancies and multidrug-resistant organisms: Special considerations and challenges. Clin Lymphoma Myeloma Leuk. 2014; 14 Suppl: S104-10.

Bevans M, Tierney DK, Bruch C, et al. Hematopoietic stem cell transplantation nursing: a practice variation study. Oncol Nurs Forum. 2009; 36(6):E317-25.

Hicheri Y, Einsele H, Martino R, et al. Environmental prevention of infection in stem cell transplant recipients: a survey of the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Transpl Infect Dis. 2013; 15(3):251-8.

Lee SJ, Astigarraga CC, Eapen M, et al. Variation in supportive care practices in hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation; 2008. 14(11): 1231-38.

Tecchio C, Bonetto C, Bertani M, et al. Predictors of anxiety and depression in hematopoietic stem cell transplant patients during protective isolation. Psycho-Oncology; 2013. 22(8): 1790-7.

Prieto JM, Atala J, Blanch J, et al. Patient-rated emotional and physical functioning among hematologic cancer patients during hospitalization for stem-cell transplantation. Bone Marrow Transplant. 2005; 35(3): 307-14.

Vottero B, Rittenmeyer L. The hospitalised patients’ experience of being in protective/source isolation: a systematic review of qualitative evidence. JBI Libr Syst Rev. 2012; 10(16):935-976

Biagioli V, Piredda M, Alvaro R, et al. The experiences of protective isolation in patients undergoing bone marrow or haematopoietic stem cell transplantation: systematic review and metasynthesis. Eur J Cancer Care (Engl). 2017; 26(5).

Dunn E, Arber A, Gallagher A. The immediacy of illness and existential crisis: patients' lived experience of under-going allogeneic stem cell transplantation for haematological malignancy. A phenomenological study. Eur J Oncol Nurs. 2016; 21:90-6

Zamanzadeh V, Valizadeh L, Sayadi L, et al. Life in limbo: experiences of Iranian hematopoietic stem cell transplantation recipient patients and nurses in a qualitative study. Int J Hematol Oncol Stem Cell Res. 2013; 7(3):25-33.

Biagioli V, Piredda M, Mauroni MR, et al. The lived experience of patients in protective isolation during their hospital stay for allogeneic haematopoietic stem cell transplantation. Eur J Oncol Nurs. 2016; 24: 79-86

Tichelli A, Labopin M, Rovó A, et al. Increase of suicide and accidental death after hematopoietic stem cell transplantation: A cohort study on behalf of the Late Effects Working Party of the European Group for Blood and Marrow Transplantation (EBMT). Cancer; 2013. 119(11): 2012-21.

Molassiotis A. Further evaluation of a scale to sceen for risk of emotional difficulties in bone marrow transplant recipients. J Adv Nurs. 1999; 29(4):922-7.

Faucher C, Le Corroller Soriano AG, Esterni B, et al. Randomized study of early hospital discharge following autologous blood SCT: medical outcomes and hospital costs. Bone marrow transplant; 2012. 47(4): 549-55.

Bergkvist K, Larsen J, Johansson UB, et al. Hospital care or home care after allogeneic hematopoietic stem cell transplantation – Patients' experiences of care and support. Eur J Oncol Nurs. 2013; 17(4):389-95.

Fernández-Avilés F, Carreras E, Urbano-Ispizua A, et al. Case-control comparison of at-home to total hospital care for autologous stem-cell transplantation for hematologic malignancies J Clin Oncol. 2006; 24(30): 4855-61.

Paul TM, Liu SV, Chong EA, et al. Outpatient autologous stem cell transplantation for patients with myeloma. Clin Lymphoma Myeloma Leuk. 2015; 15(9):536-40.

Mank AP, Schoonenberg C, Bleeker K, et al. Early discharge after high dose chemotherapy is safe and feasible: a prospective evaluation of 6 years of home care. Leuk Lymphoma. 2015; 56(7):2098-104

Schulmeister L, Quiett K, Mayer K. Quality of life, quality of care, and patient satisfaction: perceptions of patients undergoing outpatient autologous stem cell transplantation. Oncol Nurs Forum. 2005; 32(1):57-67.

Svendsen L.F.H. A philosophy of boredom. 6th edn. Reaktion Books: London, UK, 2005.

Karhe L, Kaunonen M. Patient experiences of loneliness: An evolutionary concept analysis. ANS Adv Nurs Sci. 2015; 38(4):E21-34.

Ustinova KI, Leonard WA, Cassavaugh ND, et al. Development of a 3D immersive videogame to improve arm-postural coordination in patients with TBI. J Neuroeng Rehabil. 2011; 8:61.

Sasaki T, Akaho R, Sakamaki H, et al. Mental disturbances during isolation in bone marrow transplant patients with leukemia. Bone Marrow Transplant. 2000; 25(3):315-8.

Beattie S, Lebel S, Tay J. The influence of social support on hematopoietic stem cell transplantation survival: a systematic review of literature. PLoS One. 2013; 8(4): e61586.

Bergenthal N, Will A, Streckmann F, et al. Aerobic physical exercise for adult patients with haematological malignancies. Cochrane Database Syst Rev. 2014 ;( 11):CD009075

Van Haren IE, Timmerman H, Potting CM, et al. Physical exercise for patients undergoing hematopoietic stem cell transplantation: systematic review and meta-analyses of randomized controlled trials. Phys Ther. 2013; 93(4):514-28.

Saposnik G, Mamdani M, Bayley M, et al. Effectiveness of virtual reality using Wii gaming technology in stroke rehabilitation. Int J Stroke. 2010; 5(1):47-51.

Files
IssueVol 11, No 4 (2017) QRcode
SectionArticles
Keywords
Patient isolation Social isolation Hematopoietic stem cell transplantation Time perception

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Annibali O, Pensieri C, Tomarchio V, Biagioli V, Pennacchini M, Tendas A, Tambone V, Tirindelli MC. Protective Isolation for Patients with Haematological Malignancies: A Pilot Study Investigating Patients’ Distress and Use of Time. Int J Hematol Oncol Stem Cell Res. 2017;11(4):313-318.