Adrenal Insufficiency in Patients with Beta-Thalassemia Major in the Southeast of Iran


Beta-thalassemia is a hereditary blood disorder in which the synthesis of the hemoglobin beta chain is halted or severely diminished, chiefly due to genetic mutations. As of today, the province of Sistan and Baluchistan has the highest prevalence of this disease in the southeast of Iran, with about 3,000 thalassemia patients. Adrenal dysfunction has been reported to arise in patients with beta-thalassemia major due to iron deposition in adrenal glands. We aimed to determine the prevalence of adrenal insufficiency in children with β-thalassemia major, who had been referred to Ali Asghar Hospital, Zahedan, prior to the time of the study.

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IssueVol 16, No 3 (2022) QRcode
DOI https://doi.org/10.18502/ijhoscr.v16i3.10140
Adrenal insufficiency; Beta-thalassemia; Cosyntropin; Cortisol

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How to Cite
Miri-Aliabad G, Nakhaie Moghadam M, Naderi M, Saravani M, Saravani R, Sargazi S, Shirvaliloo M. Adrenal Insufficiency in Patients with Beta-Thalassemia Major in the Southeast of Iran. Int J Hematol Oncol Stem Cell Res. 2022;16(3):174-176.