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Primary hyperaldostronisim as initial presentation of adrenal cortical carcinoma with liver metastasis: a case report

Abstract

Adrenocortical carcinoma (ACC) is a rare tumor and usually a fatal disease which can develop at any age in either sex. Differential diagnosis between malignant and benign adrenal mass is not easy which leads to significant clinical challenge for optimal treatment. Here we report a 22-year-old woman diagnosed with primary hyper aldostronism initially but disease relapsed during six months and magnetic resonance imaging revealed tumor with metastasis to the liver.

Kopf D, Goretzki PE, Lehnert H. Clinical managment of malignant arenal tumors. J Cancer Res Clin Oncol. 2001; 127: 143-155.

Wooten MD, King DK. Adrenal cortical carcinoma. Epidemiology and treatment with mitotane and a review of the literature. Cancer 1993;72:3145-55.

Stratakis CA, Chrousos GP: Adrenal cancer. Endocrinol Metab Clin North Am 2000; 29:15-25.

Ng L, Libertino JM. Adrenocortical carcinoma: diagnosis, evaluation and treatment. J Urol 2003; 169:5-11.

Dackiw AP, Lee JE, Gagel RF, Evans DB. Adrenal cortical carcinoma. World J Surg 2001; 25:914-26.

Icard P, Chapuis Y, Andreassian B, Bernard A, Proye C. Adrenocortical carcinoma in surgically treated patients: a retrospective study on 156 cases by the French Association of Endocrine Surgery. Surgery. 1992; 112:972-979.

Schulick RD, Brennan MF. Long-term survival after complete resection and repeat resection in patients with adrenocortical carcinoma. Ann Surg Oncol 1999;6:719-

Wajchenberg BL, Albergaria Pereira MA, Medonca BB. Adrenocortical carcinoma: clinical and laboratory observations. Cancer 2000; 88:711-36.

SILVERBERG's principles & practice of surgical pathology & cytopathology, page 2187, volume 2; 2006, C HURCHILL LIVING STONE, ELSEVIER.

Norton JA, Le HN. Adrenal tumors. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: principles and practice of oncology. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2000:1770-1771.

Szczeklik A, ed. Choroby wewnętrzne. Tom 1. Kraków, Medycyna Praktyczna, 2006:1143.

Justyna Gil, Marta Kalembkiewicz, Edyta Polak, Marta Kostecka-Matyja. Disseminated adrenocortical carcinoma: case report. Pol Arch Med Wewn. 2007; 117 (7): 317-321

Allolio B, Fassnacht M. Clinical review: Adrenocortical carcinoma: clinical update. J Clin Endocrinol Metab 2006; 91:2027-2037.

Sreelatha Chalasani, MD, MPH; Hemender Singh Vats, MD;Tarit K. Banerjee, MD, FACP; and Alan K. McKenzie, MD. Metastatic Virilizing Adrenocortical Carcinoma:A Rare Case of Cure with Surgery and Mitotane Therapy. Clinical Medicine & Research,Volume 7, Number 1/2: 48-51

Grumbach MM, Biller BM, Braunstein GD, Campbell KK, Carney JA, Godley PA, Harris EL, Lee JK, Oertel YC, Posner MC, Schlechte JA, Wieand HS. Management of the clinically inapparent adrenal mass (“incidentaloma”). Ann Intern Med 2003; 138:424-429.

Kasperlik-Zaluska AA, Migdalska BM, Makowska, AM. Incidentally found adrenocortical carcinoma. A study of 21 patients. Eur J Cancer. 1988 34, 1721-1724.

Barzon L, Sonino N, Fallo F, et al. Prevalence and natural history of adrenal incidentalomas. Eur J Endocrinol 2003; 149:273-85.

Xichun S, Alberto A, Claudia Y.Castro. Adrenal cortical carcinoma with Concomitant Myelolipoma in a Patient with Hyperaldosteronism .Archives of Pathology and Laboratory Medicine; 129:6.p144-7

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IssueVol 7, No 2 (2013) QRcode
SectionArticles
Keywords
Adrenocortical carcinoma Liver metastases Surgery

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How to Cite
1.
Aghamohammadzadeh N, Faraji A, Bozorgi F, Faraji I, Moghadaszadeh M. Primary hyperaldostronisim as initial presentation of adrenal cortical carcinoma with liver metastasis: a case report. Int J Hematol Oncol Stem Cell Res. 1;7(2):37-41.